Publications
Filter by topic:
Flow augmentation STA-MCA bypass evaluation for patients with acute stroke and unilateral large vessel occlusion: a proposal for an urgent bypass flowchart
Sebök M, Esposito G, Niftrik CHBV, Fierstra J, Schubert T, Wegener S, Held J, Kulcsár Z, Luft AR, Regli L.
J Neurosurg. 2022 Jan 7:1-9.
Cerebrovascular disease
Crossed Cerebellar Diaschisis Indicates Hemodynamic Compromise in Ischemic Stroke Patients
von Bieberstein L, van Niftrik CHB, Sebök M, El Amki M, Piccirelli M, Stippich C, Regli L, Luft AR, Fierstra J, Wegener S.
Transl Stroke Res. 2021 Feb;12(1):39-48.
Cerebrovascular disease
Crossed Cerebellar Diaschisis in Patients With Symptomatic Unilateral Anterior Circulation Stroke Is Associated With Hemodynamic Impairment in the Ipsilateral MCA Territory
Sebök M, van Niftrik CHB, Piccirelli M, Muscas G, Pangalu A, Wegener S, Stippich C, Regli L, Fierstra J.
J Magn Reson Imaging. 2021 Apr;53(4):1190-1197.
Cerebrovascular disease
Flow-augmentation bypass in the treatment of acute ischemic stroke
Guida L, Sebök M, Wegener S, Fierstra J, van Niftrik B, Luft AR, Regli L, Esposito G.
J Neurosurg Sci. 2021 Jun;65(3):269-276.
Revascularization surgery
Clinical
Increased Ipsilateral Posterior Cerebral Artery P2-Segment Flow Velocity Predicts Hemodynamic Impairment
van Niftrik CHB, Sebök M, Wegener S, Esposito G, Halter M, Hiller A, Stippich C, Luft AR, Regli L, Fierstra J.
Stroke. 2021 Apr;52(4):1469-1472.
Cerebrovascular disease
Distinct Cerebrovascular Reactivity Patterns for Brain Radiation Necrosis
Muscas G, van Niftrik CHB, Sebök M, Della Puppa A, Seystahl K, Andratschke N, Brown M, Weller M, Regli L, Piccirelli M, Fierstra J.
Cancers (Basel). 2021 Apr 13;13(8):1840.
Brain tumor
Topographic volume-standardization atlas of the human brain
Akeret K, van Niftrik CHB, Sebök M, Muscas G, Visser T, Staartjes VE, Marinoni F, Serra C, Regli L, Krayenbühl N, Piccirelli M, Fierstra J.
Brain Struct Funct. 2021 Jul;226(6):1699-1711.
Neuroimaging
Intraoperative BOLD-fMRI Cerebrovascular Reactivity Assessment
Muscas G, van Niftrik CHB, Sebök M, Esposito G, Regli L, Fierstra J.
Acta Neurochir Suppl. 2021;132:139-143.
Neuroimaging
Hypermetabolism and impaired cerebrovascular reactivity beyond the standard MRI-identified tumor border indicate diffuse glioma extended tissue infiltration
Sebök M, van Niftrik CHB, Muscas G, Pangalu A, Seystahl K, Weller M, Regli L, Fierstra J.
Neurooncol Adv. 2021 Mar 30;3(1):vdab048.
Brain tumor
Mapping Cerebrovascular Reactivity Impairment in Patients With Symptomatic Unilateral Carotid Artery Disease
Sebök M, van Niftrik CHB, Winklhofer S, Wegener S, Esposito G, Stippich C, Luft A, Regli L, Fierstra J.
J Am Heart Assoc. 2021 Jun 15;10(12):e020792.
Cerebrovascular disease
Leptomeningeal collateral activation indicates severely impaired cerebrovascular reserve capacity in patients with symptomatic unilateral carotid artery occlusion
Sebök M, Niftrik CHBV, Lohaus N, Esposito G, Amki ME, Winklhofer S, Wegener S, Regli L, Fierstra J.
J Cereb Blood Flow Metab. 2021 Nov;41(11):3039-3051.
Cerebrovascular disease
Agreement of novel hemodynamic imaging parameters for the acute and chronic stages of ischemic stroke: a matched-pair cohort study
Sebök M, van Niftrik CHB, Wegener S, Luft A, Regli L, Fierstra J.
Neurosurg Focus. 2021 Jul;51(1):E12.
Cerebrovascular disease
Measuring Cerebrovascular Reactivity: Sixteen Avoidable Pitfalls
Sobczyk O, Fierstra J, Venkatraghavan L, Poublanc J, Duffin J, Fisher JA, Mikulis DJ.
Front Physiol. 2021 Jul 7;12:665049.
Cerebrovascular disease
Validation of the Clavien-Dindo grading system of complications for microsurgical treatment of unruptured intracranial aneurysms
Sebök M, Blum P, Sarnthein J, Fierstra J, Germans MR, Serra C, Krayenbühl N, Regli L, Esposito G.
Neurosurg Focus. 2021 Nov;51(5):E10.
Cerebrovascular disease
Machine Learning Algorithms in Neuroimaging: An Overview
Stumpo V, Kernbach JM, van Niftrik CHB, Sebök M, Fierstra J, Regli L, Serra C, Staartjes VE.
Acta Neurochir Suppl. 2022;134:125-138.
Machine learning
Feasibility of glioblastoma tissue response mapping with physiologic BOLD imaging using precise oxygen and carbon dioxide challenge
Stumpo V, Sebök M, van Niftrik CHB, Seystahl K, Hainc N, Kulcsar Z, Weller M, Regli L, Fierstra J.
MAGMA. 2021 Dec 7.
Brain tumor
Delayed cerebral atrophy after cerebellar stroke: topographical relation and clinical impact
van Niftrik CHB, Visser TF, Sebök M, Muscas G, El Amki M, Serra C, Regli L, Wegener S, Fierstra J.
Brain Commun. 2021 Nov 24;3(4):fcab279.
Cerebrovascular disease
Characterizing ipsilateral thalamic diaschisis in symptomatic cerebrovascular steno-occlusive patients
Hendrik Bas van Niftrik C, Sebök M, Muscas G, Piccirelli M, Serra C, Krayenbühl N, Pangalu A, Bozinov O, Luft A, Stippich C, Regli L, Fierstra J.
J Cereb Blood Flow Metab. 2020 Mar;40(3):563-573.
Cerebrovascular disease
Hemodynamic investigation of peritumoral impaired blood oxygenation-level dependent cerebrovascular reactivity in patients with diffuse glioma
Muscas G, van Niftrik CHB, Sebök M, Seystahl K, Piccirelli M, Stippich C, Weller M, Regli L, Fierstra J.
Magn Reson Imaging. 2020 Jul;70:50-56.
Brain tumor
Crossed Cerebellar Diaschisis in Patients with Diffuse Glioma Is Associated with Impaired Supratentorial Cerebrovascular Reactivity and Worse Clinical Outcome
Sebök M, van Niftrik CHB, Halter M, Hiller A, Seystahl K, Pangalu A, Weller M, Stippich C, Regli L, Fierstra J.
Cerebellum. 2020 Dec;19(6):824-832.
Brain tumor
Feasibility and safety of intraoperative BOLD functional MRI cerebrovascular reactivity to evaluate extracranial-to-intracranial bypass efficacy
Muscas G, Bas van Niftrik CH, Fierstra J, Piccirelli M, Sebök M, Burkhardt JK, Valavanis A, Pangalu A, Regli L, Bozinov O.
Neurosurg Focus. 2019 Feb 1;46(2):E7.
Cerebrovascular disease
Revascularization surgery
Neuroimaging
The voxel-wise analysis of false negative fMRI activation in regions of provoked impaired cerebrovascular reactivity
van Niftrik CHB, Piccirelli M, Muscas G, Sebök M, Fisher JA, Bozinov O, Stippich C, Valavanis A, Regli L, Fierstra J.
PLoS One. 2019 May 6;14(5):e0215294.
Neuroimaging
Diffuse gliomas exhibit whole brain impaired cerebrovascular reactivity
Fierstra J, van Niftrik C, Piccirelli M, Bozinov O, Pangalu A, Krayenbühl N, Valavanis A, Weller M, Regli L.
Magn Reson Imaging. 2018 Jan;45:78-83.
Brain tumor
Staging Hemodynamic Failure With Blood Oxygen-Level-Dependent Functional Magnetic Resonance Imaging Cerebrovascular Reactivity: A Comparison Versus Gold Standard ((15)O-)H(2)O-Positron Emission Tomography
Fierstra J, van Niftrik C, Warnock G, Wegener S, Piccirelli M, Pangalu A, Esposito G, Valavanis A, Buck A, Luft A, Bozinov O, Regli L.
Stroke. 2018 Mar;49(3):621-629.
Neuroimaging
Cerebrovascular disease
Impact of baseline CO(2) on Blood-Oxygenation-Level-Dependent MRI measurements of cerebrovascular reactivity and task-evoked signal activation
van Niftrik CHB, Piccirelli M, Bozinov O, Maldaner N, Strittmatter C, Pangalu A, Valavanis A, Regli L, Fierstra J.
Magn Reson Imaging. 2018 Jun;49:123-130.
Neuroimaging
BOLD cerebrovascular reactivity as a novel marker for crossed cerebellar diaschisis
Sebök M, van Niftrik CHB, Piccirelli M, Bozinov O, Wegener S, Esposito G, Pangalu A, Valavanis A, Buck A, Luft AR, Regli L, Fierstra J.
Neurology. 2018 Oct 2;91(14):e1328-e1337.
Cerebrovascular disease
Blood oxygen-level dependent functional assessment of cerebrovascular reactivity: Feasibility for intraoperative 3 Tesla MRI
Fierstra J, Burkhardt JK, van Niftrik CH, Piccirelli M, Pangalu A, Kocian R, Neidert MC, Valavanis A, Regli L, Bozinov O.
Magn Reson Med. 2017 Feb;77(2):806-813.
Neuroimaging
Iterative analysis of cerebrovascular reactivity dynamic response by temporal decomposition
van Niftrik CHB, Piccirelli M, Bozinov O, Pangalu A, Fisher JA, Valavanis A, Luft AR, Weller M, Regli L, Fierstra J.
Brain Behav. 2017 Jul 26;7(9):e00705.
Neuroimaging
Altered intraoperative cerebrovascular reactivity in brain areas of high-grade glioma recurrence
Fierstra J, van Niftrik B, Piccirelli M, Burkhardt JK, Pangalu A, Kocian R, Valavanis A, Weller M, Regli L, Bozinov O.
Magn Reson Imaging. 2016 Jul;34(6):803-808.
Neuroimaging
Brain tumor
Fine tuning breath-hold-based cerebrovascular reactivity analysis models
van Niftrik CH, Piccirelli M, Bozinov O, Pangalu A, Valavanis A, Regli L, Fierstra J.
Brain Behav. 2016 Jan 25;6(2):e00426.
Neuroimaging
Methodological aspect
Neuroimaging Assessment of Cerebrovascular Reactivity in Concussion: Current Concepts, Methodological Considerations, and Review of the Literature
Ellis MJ, Ryner LN, Sobczyk O, Fierstra J, Mikulis DJ, Fisher JA, Duffin J, Mutch WA.
Front Neurol. 2016
Traumatic brain injury
Temporal Profile of Cerebrovascular Reactivity Impairment, Gray Matter Volumes, and Persistent Symptoms after Mild Traumatic Head Injury
da Costa L, van Niftrik CB, Crane D, Fierstra J, Bethune A.
Front Neurol. 2016 May 11;7:70.
Traumatic brain injury
Early identification of brain tissue at risk for delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage
da Costa L, Fisher J, Mikulis DJ, Tymianski M, Fierstra J.
Acta Neurochir Suppl. 2015;120:105-9.
Cerebrovascular disease
Impaired cerebrovascular reactivity in the early phase of subarachnoid hemorrhage in good clinical grade patients does not predict vasospasm
da Costa L, Houlden D, Rubenfeld G, Tymianski M, Fisher J, Fierstra J.
Acta Neurochir Suppl. 2015;120:249-53.
Cerebrovascular disease
Assessing cerebrovascular reactivity abnormality by comparison to a reference atlas
Sobczyk O, Battisti-Charbonney A, Poublanc J, Crawley AP, Sam K, Fierstra J, Mandell DM, Mikulis DJ, Duffin J, Fisher JA.
J Cereb Blood Flow Metab. 2015 Feb;35(2):213-20.
Neuroimaging
Methodological aspect
BOLD MRI and early impairment of cerebrovascular reserve after aneurysmal subarachnoid hemorrhage
da Costa L, Fierstra J, Fisher JA, Mikulis DJ, Han JS, Tymianski M.
J Magn Reson Imaging. 2014 Oct;40(4):972-9.
Cerebrovascular disease
Non-invasive accurate measurement of arterial PCO2 in a pediatric animal model
Fierstra J, Winter JD, Machina M, Lukovic J, Duffin J, Kassner A, Fisher JA.
J Clin Monit Comput. 2013 Apr;27(2):147-55.
Methodological aspect
Impaired peri-nidal cerebrovascular reserve in seizure patients with brain arteriovenous malformations
Fierstra J, Conklin J, Krings T, Slessarev M, Han JS, Fisher JA, Terbrugge K, Wallace MC, Tymianski M, Mikulis DJ.
Brain. 2011 Jan;134(Pt 1):100-9.
Cerebrovascular disease
Surgical revascularization reverses cerebral cortical thinning in patients with severe cerebrovascular steno-occlusive disease
Fierstra J, Maclean DB, Fisher JA, Han JS, Mandell DM, Conklin J, Poublanc J, Crawley AP, Regli L, Mikulis DJ, Tymianski M.
Stroke. 2011 Jun;42(6):1631-7.
Cerebrovascular disease
Revascularization surgery
End-inspiratory rebreathing reduces the end-tidal to arterial PCO2 gradient in mechanically ventilated pigs
Fierstra J, Machina M, Battisti-Charbonney A, Duffin J, Fisher JA, Minkovich L.
Intensive Care Med. 2011 Sep;37(9):1543-50.
Methodological aspect
Severely impaired cerebrovascular reserve in patients with cerebral proliferative angiopathy
Fierstra J, Spieth S, Tran L, Conklin J, Tymianski M, ter Brugge KG, Fisher JA, Mikulis DJ, Krings T.
J Neurosurg Pediatr. 2011 Sep;8(3):310-5.
Cerebrovascular disease
Steal physiology is spatially associated with cortical thinning
Fierstra J, Poublanc J, Han JS, Silver F, Tymianski M, Crawley AP, Fisher JA, Mikulis DJ.
J Neurol Neurosurg Psychiatry. 2010 Mar;81(3):290-3.
Cerebrovascular disease
Neuroimaging